Tag Archives: sodium channel

Inability to experience pain

Voltage-gated sodium channels produce action potentials that carry pain sensation into the central nervous system. Here is an article about a family with members who exhibit a congenital inability to experience pain: A stop codon mutation in SCN9A causes lack … Continue reading

Posted in congenital insensitivity to pain, Diseases, electrophysiology, NaV1.7, pharmacology, ranolazine | Tagged , | Leave a comment

Pain sensation and sodium channels

  Panamanian golden frog This blog post is on the trail of potential new treatments for chronic pain conditions. NaV1.8 is one of the types of voltage-gated sodium channels present in pain sensory neurons. Several types of ion channels have … Continue reading

Posted in electrophysiology, NaV1.8, pain | Tagged , , , | 1 Comment